qhd43415_15

Name of Target: 
2'-O-methyltransferase (2'-O-MT).
Function: 
Methyltransferase that mediates mRNA cap 2'-O-ribose methylation to the 5'-cap structure of viral mRNAs. N7-methyl guanosine cap is a prerequisite for binding of nsp16. Therefore plays an essential role in viral mRNAs cap methylation which is essential to evade immune system.
Ramchandran Plot: